Protein Alignment mars and Dlgap5

DIOPT Version :10

• Sequence 1: NP_610878.1
• Gene: mars / 36498
• FlyBaseID: FBgn0033845
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: NP_001129274.1
• Gene: Dlgap5 / 289997
• RGDID: 1311247
• Length: 815
• Species: Rattus norvegicus
• Alignment Length: 949
• Identity: 191/949 - (20%)
• Similarity: 306/949 - (32%)
• Gaps: 368/949 - (38%)

  Fly    22 QENRDRLQAARAKKREDCFYQNRIISVSPTPVKIK-----QLAAAQAALTQENVAPKLESPERLD 81
            :|||.|:           :.:||...:....|.::     .:......||.||.:.|
  Rat    32 KENRHRV-----------YERNRHFGLRDVNVPLEGRDLVNIHEMSQDLTLENASSK-------- 77

  Fly    82 TKPAELLKESNPKVSRQKLYLQRYMEWK-IAKTKEHKQQDQKRRGAAINVPTVKQSKALPKSQTF 145
            ||..:::..     .::|..||:|.|.| :.|.||.::                      |::.|
  Rat    78 TKSVKMVLS-----DQRKQLLQKYKEEKQLQKLKEQRE----------------------KAKVF 115

  Fly   146 RVPDNLASAKQKEAAPMFQPPKRCSLYMIANPTGKGKAAEPIKPSIPKPTSAAAPPSSNTVAASS 210
            :|      ...:.|||.|         ::|:.  :|..|||.|          |.|.:..:..|.
  Rat   116 KV------GLYRPAAPGF---------LVADQ--RGVKAEPQK----------AFPYTGRITRSK 153

  Fly   211 ALARHKSAASATKIVPAI-----RQNNNPVALARQKAAARPI-PNTTKQTTSVRQPGIEAKKITT 269
            |....:.:.:.::.:|..     ||.:....|.|:|...:|: |.:.|...||.... .||::..
  Rat   154 ARDHMEQSKTGSRNIPQAAQFGQRQISEKKPLDREKKVMQPMGPTSGKAAGSVAATQ-RAKQMAG 217

  Fly   270 TIPRPTPATVTKAKTPGIRQQPPVVSTKPRLPEPPAPRTARLPNVLSKPFEKPLGNKAPVTRRAN 334
            |:|..|...||:|.                                         |:....||.
  Rat   218 TVPSTTRKPVTRAT-----------------------------------------NENGSERRG- 240

  Fly   335 VVKPQPIRGGGGAAAKFKDTAGATSKAASHSIRMKATKIKSQYTRLQDNVRKLPQLKAELLHAAT 399
                 |.||.....|:     |...|.           |.||...|....:.|
  Rat   241 -----PSRGRPAGKAE-----GELDKI-----------ISSQGIALGSEEKHL------------ 272

  Fly   400 LDIPPLTPLDDIHNPFIDQATSTQCKSNNSSGHLLEAFGDTILLSPVAPVKA-EGESSVKRQLL- 462
                                     :|.:|..:.:|:..:|:      |.|. |.||....:..
  Rat   273 -------------------------QSQSSVTNEVESLQETV------PAKGRERESFAPERCAF 306

  Fly   463 --PEGKKEASGPVAKKKFDFTRYSVAN-SPAEDSLILDPQ--------QTTVKEDTGDSTLVPEG 516
              |.|.|              .|.||. ||...:..|.|.        :....:||.:..||
  Rat   307 QPPRGLK--------------TYQVAPLSPRSANAFLTPSCDWNHLRPEVATAQDTANEVLV--- 354

  Fly   517 TKTPPRRESNGMPNYLSPFVSVSRGKVNSRCEKEKR-----------NSFYL------SNEESPL 564
                 ::|||           .|:..::|:.:..|.           ||.:|      |:|....
  Rat   355 -----QQESN-----------KSQFGLDSQTDSRKERGLNQKDASTPNSDHLSVKGITSSEAGDG 403

  Fly   565 EVRRAIESVLYFRLQLENEITRLQALCAEWEAYSKENEARLQETGGIDMINVTIGQTRLLTTKKM 629
            :..:....|.|||..|::|..||.:.|.:||   |:.|..:.:... |:|...:||||||..::.
  Rat   404 QTGQPQHDVPYFRKILQSETDRLNSHCLDWE---KKLELDIPDDAK-DLIRTAVGQTRLLIMERF 464

  Fly   630 MQFSGLIDRCEAGATGKNSQPNDGSEDSKPVQAEDLEGWWDMLRLQSENVDKRFDNLKRWKANDW 694
            .||.||:|.||.            ....|.....||:|:|||:..|.::|.::|:||.:.:.:.|
  Rat   465 RQFEGLVDNCEY------------KRGEKETTCTDLDGFWDMVSFQVDDVTQKFNNLMKLEESGW 517

  Fly   695 LDPDAVAEEPKQPKPKPKISRNMKIKSKAKPSSNLQQFLRKAHANMKKTKVEEPTLEDGLPATSS 759
            .|.:         .|..|:     |:.|..|.              |.:|.::.  |||..|..|
  Rat   518 KDNN---------NPSKKV-----IRKKIVPG--------------KTSKAKQD--EDGRTAARS 552

  Fly   760 RHSSPRVIVVRNRRSFSPARTVLRMSTGEGRQSIAPNALLKSAILAAAEQNAAKTPPPKPRTSIL 824
                 |:..::|                          .:|..:...|:..||....|.....|:
  Rat   553 -----RLAAIKN--------------------------AMKDRLRQEAQAQAAVPEIPTAADKIV 586

  Fly   825 KTPGTTKRQNRGVLFSAKKSVRRFQF--------TYEEGNISND--------------------- 860
            ...|..:.::....||...|.||.||        ...||..:.|
  Rat   587 FDAGFFRIESPVKSFSVLSSERRSQFGAHVSASRAVPEGRAAGDLLRQKTPLKRPDPQSSTIEHV 651

  Fly   861 ETVGADKLED-CE--EDMSLEASTESGSLEQNPGRDSNQ 896
            :...:|.||. |.  ||:......:|..:|    ||.|:
  Rat   652 DRTFSDGLESRCSQVEDILCPVQQDSSDVE----RDVNK 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_610878.1	PHA03247	<131..342	CDD:223021	40/216 (19%)
		GKAP	<580..>694	CDD:460897	36/113 (32%)
Dlgap5	NP_001129274.1	GKAP	<414..580	CDD:460897	59/242 (24%)