Protein Alignment mars and Dlgap1

DIOPT Version :9

• Sequence 1: NP_001163142.1
• Gene: mars / 36498
• FlyBaseID: FBgn0033845
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_006524231.1
• Gene: Dlgap1 / 224997
• MGIID: 1346065
• Length: 1030
• Species: Mus musculus
• Alignment Length: 896
• Identity: 176/896 - (19%)
• Similarity: 310/896 - (34%)
• Gaps: 293/896 - (32%)

  Fly     1 MQRHKELYK------EQSLVLSPRNHCQENRDRLQAARAKKREDCFYQNRIISVSPTPVKIKQLA 59
            :.|.:|:|:      :|::|.|  ..||:.|. .|..::|.:....:.::::.     ||:|.:.
Mouse   291 VSRAREVYQKASVNMDQAMVKS--EACQQERS-CQYLQSKLKRIQGHLSQVVF-----VKVKAVW 347

  Fly    60 AAQAALTQENVAPKLESPE------------------RL-----------------DTKPAELLK 89
            :.:|.|.......:...|:                  |:                 ||.|
Mouse   348 SRKAVLPATKKMRRSRVPQDEWSGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSP----- 407

  Fly    90 ESNPKV-SRQKLYLQ----RYMEWKIAK-TKEHKQQDQKRRGAAINVPTVKQSKALPKSQTFRVP 148
            :.:||| :|::.||:    ...|....| :.||..:.|.|..:.:        :|:.:....|..
Mouse   408 KPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYL--------RAVSEVSINRSL 464

  Fly   149 DNLASAKQKEAAPMFQPPK---RCSLYMIANPT----------G-------------KGKAAEPI 187
            |:|      :.|.:...||   |...||.|..|          |             :.:|.|.:
Mouse   465 DSL------DPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEAL 523

  Fly   188 KPSIPKPTSAAAPPSSNTVAASSALARHKSAASATKIVPAIRQNNNPVALARQKAAARPIPNTTK 252
              .:|.|                ...|.:|.:....|.....|::..|:|   ::::.|     :
Mouse   524 --DLPLP----------------GCFRMRSHSYVRAIEKGCSQDDECVSL---RSSSPP-----R 562

  Fly   253 QTTSVR--QPGIEAKKITTTIPRPTPATVTKAKTPGIRQQPPVVSTKPRLPEPPAPRTARLPNVL 315
            .||:||  |......|:::.:...:..|..| |||                 ||.|     |...
Mouse   563 TTTTVRTIQSSTGVIKLSSAVEVSSCITTYK-KTP-----------------PPVP-----PRTT 604

  Fly   316 SKPFEKPLGNKAPVTRRANVVKPQPIRGGGGAAAKFKDTAGATSKAASHSIRMKATKIKSQYTRL 380
            :|||       ..:|.:::....|.         .:.|..|......|.|             .|
Mouse   605 TKPF-------ISITAQSSTESAQD---------AYMDGQGQRGDMISQS-------------GL 640

  Fly   381 QDNVRKLPQLKA--ELLHAATLDIPPLTPLDDIHNPFIDQATSTQCKSNNSSGHLLEAFGDTILL 443
            .::...|..:||  ..:.||..         .||.|      ::|...:|::     |...|..:
Mouse   641 SNSTESLDSMKALTAAIEAANA---------QIHGP------ASQHMGSNAA-----AVTTTTTI 685

  Fly   444 SPVAPVKAEGESSVKRQLL----------PE--------GKKEASGPVAKKKFDFTRYSVANS-- 488
            :.|.....:.:....|.|.          ||        .|.::.|...:::..|.|::.:||
Mouse   686 ATVTTEDRKKDFKKNRCLSIGIQVDDAEEPEKMAESKTSNKFQSVGVQVEEEKCFRRFTRSNSVT 750

  Fly   489 ------------------PAEDSLILDPQQTTVKEDTGDSTLVPEGT-------KTPPRRESNGM 528
                              ..||:....|.......|...||:..:|:       ......:::..
Mouse   751 TAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFD 815

  Fly   529 PNYLSPFVSVSRGKVNSRCEKEKRNSFYLSNEESPLE-VRRAI--ESVLYFRLQLENEITRLQAL 590
            |:.|.|                 .:.:..|..|.||| |:|::  ....:|...|:.|..|::..
Mouse   816 PSILPP-----------------PDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGW 863

  Fly   591 CAEWEAYSKENEARLQETGGIDMINVTIGQTRLLTTKKMMQFSGLIDRCEAGATGKNSQPNDGSE 655
            |...|...:||.......|   .|...:|..:||..:|..||..|   ||     :|..||   .
Mouse   864 CKLMEREERENNLPEDILG---KIRTAVGSAQLLMAQKFYQFREL---CE-----ENLNPN---A 914

  Fly   656 DSKPVQAEDLEGWWDMLRLQSENVDKRFDNLKRWKANDWLDPDAV-AEEPKQPKPKPK------- 712
            ..:|. ::||.|:||||:|..||:..:||.|.:.|||:|...|.: .:|.:.|.|.||
Mouse   915 HPRPT-SQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPA 978

  Fly   713 -ISRNMKIKSKAKPSSNLQQFLRKAHANMKKTKVEE--PTLEDGLPATSSR 760
             :.|...::|..:..:..:....|..|::::....|  .::|..:|...:|
Mouse   979 PLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTR 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_001163142.1	GKAP	<558..>703	CDD:281368	48/148 (32%)
Dlgap1	XP_006524231.1	GKAP	698..1030	CDD:367461	81/364 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3971
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910