Protein Alignment mars and Dlgap5

DIOPT Version :10

• Sequence 1: NP_610878.1
• Gene: mars / 36498
• FlyBaseID: FBgn0033845
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: NP_001411713.1
• Gene: Dlgap5 / 218977
• MGIID: 2183453
• Length: 820
• Species: Mus musculus
• Alignment Length: 942
• Identity: 198/942 - (21%)
• Similarity: 328/942 - (34%)
• Gaps: 320/942 - (33%)

  Fly    22 QENRDRLQAARAKKREDCFYQNRIISVSPTPVKIKQLAAAQAALTQENVAPKLESPERLDTKPAE 86
            :|||.|:           :.:||...:....:.::.........|.::::|:..|.:   |:..:
Mouse    32 KENRHRV-----------YERNRHFGLKDVNIPLEGRELGNIHETSQDLSPEKASSK---TRSVK 82

  Fly    87 LLKESNPKVSRQKLYLQRYMEWK-IAKTKEHKQQDQKRRGAAINVPTVKQSKALPKSQTFRVPDN 150
            ::..     .::|..||:|.|.| :.|.||  |:::.:||                  .|:|
Mouse    83 MVLS-----DQRKQLLQKYKEEKQLQKLKE--QREKAKRG------------------VFKV--- 119

  Fly   151 LASAKQKEAAPMFQPPKRCSLYMIANPTGKGKAAEPIKPSIPKPTSAAAPPSSNTVAASSALARH 215
               ...:.|||.|         ::.:.  :|..|||.|          |.|.:..:..|    :.
Mouse   120 ---GLYRPAAPGF---------LVTDQ--RGAKAEPEK----------AFPHTGRITRS----KT 156

  Fly   216 KSAASATKIVPAIRQNNNPVALARQKAAARPIPNTT---KQTTSVRQPGIEAKKITTTIPRPTPA 277
            |.....|||                  .:|.:|..|   ::.||.:||....:|:
Mouse   157 KEYMEQTKI------------------GSRNVPKATQSDQRQTSEKQPLDRERKV---------- 193

  Fly   278 TVTKAKTPGIRQQPPVVSTKPRLPEPPAPRTARL-PNVLSKPFEKPLGNKAPVTRRANVVKPQPI 341
                        ..||:.|..:..|..|.:.|:| ...:|....|      ||||..|....:.:
Mouse   194 ------------MQPVLFTSGKGTESAATQRAKLMARTVSSTTRK------PVTRATNEKGSERM 240

  Fly   342 RGGGGAAAKFKDTAGATSKAASHSIRMKATKIKSQYTRLQDNVRKLPQLKAELLHAATLDIPPLT 406
            |..||..|                                    |.|:.|.:.:      ||...
Mouse   241 RPSGGRPA------------------------------------KKPEGKPDKV------IPSKV 263

  Fly   407 PLDDIHNPFIDQATSTQCKSNNSSGHLLEAFGDTILLSPVAPVKAEGESSVKRQLLPEGKKEASG 471
            ..|:.|       ..:|.:..:..|. |..|.:...|...||  |:|:           ::::..
Mouse   264 ERDEKH-------LDSQTRETSEMGP-LGVFREVESLPATAP--AQGK-----------ERKSFA 307

  Fly   472 P---VAKKKFDFTRYSVAN-SPAEDSLILDPQ----------QTTVKEDTGDSTLVPEGTKTPPR 522
            |   |.:.......|.||. ||...:..|.|.          .:|..:|..:..||.:|.::...
Mouse   308 PKHCVFQPPCGLKSYQVAPLSPRSANAFLTPNCDWNQLRPEVFSTTTQDKANEILVQQGLESLTD 372

  Fly   523 RESNGMPNYLSPFVSVSRGKVNSRCEKEKRNSFYLS------NEESPLEVRRAIESVLYFRLQLE 581
            |....:.|        .:|...|       :|.:.|      :|.|..:..:....|.|||..|:
Mouse   373 RSKEHVLN--------QKGASTS-------DSNHASVKGVPCSEASEGQTSQPPHDVPYFRKILQ 422

  Fly   582 NEITRLQALCAEWEA---YSKENEARLQETGGIDMINVTIGQTRLLTTKKMMQFSGLIDRCEAGA 643
            :|..||.:.|.|||.   ....:||:       .:|..|:||||||..::..||.||:|.||.
Mouse   423 SETDRLTSHCQEWEGKLDLDIPDEAK-------GLIRTTVGQTRLLIKERFRQFEGLVDNCEY-- 478

  Fly   644 TGKNSQPNDGSEDSKPVQAEDLEGWWDMLRLQSENVDKRFDNLKRWKANDWLDPDAVAEEPKQPK 708
                      ....|.....||:|:|||:..|.::|:::|:||.:.:|:.|.|    :..|.:..
Mouse   479 ----------KRGEKETTCTDLDGFWDMVSFQVDDVNQKFNNLIKLEASGWKD----SNNPSKKV 529

  Fly   709 PKPKI-------------------SRNMKIKS--KAKPSSNLQQFLRKAHA----NMKKTKVEEP 748
            .:.||                   ||...||:  |.:|...:|     |||    |.|  :|::.
Mouse   530 LRKKIVPGRTSKAKQDDDGRAAARSRLAAIKNAMKGRPQQEVQ-----AHAAAPENTK--EVDKI 587

  Fly   749 TLEDGLPATSSRHSSPRVIVVRNRRSFSPARTVLRMSTGEGRQSIAPNALLKSAILAAAEQNAAK 813
            ..:.|.    .|..||    |::....|..|...|..|......:.|..      .||.:....|
Mouse   588 VFDAGF----FRIESP----VKSFSVLSSERRSQRFGTPLSASKVVPEG------RAAGDLLRQK 638

  Fly   814 TPPPKPRTSILKTPGTTKRQNRGVLFSAKKSVRRFQFTYEEG-----NISNDETVGADKLEDCEE 873
            .|..||      .|.::|.::          |.|   |:.:|     ::.:....|.....|.|.
Mouse   639 MPLKKP------DPQSSKSEH----------VDR---TFSDGLESRCHVEDTPCPGEQDSSDIEH 684

  Fly   874 DMS-LEASTESGSLEQN---PGRDSN-QENEA 900
            |:: :....:..|:|.|   |..|:| .:.||
Mouse   685 DVNKINVKMDCFSVETNLPLPAGDANTNQKEA 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mars	NP_610878.1	PHA03247	<131..342	CDD:223021	40/214 (19%)
		GKAP	<580..>694	CDD:460897	38/116 (33%)
Dlgap5	NP_001411713.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..282		46/258 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	377..413		7/50 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	629..654		8/40 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	735..757