DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and Frk

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_077344.1	Gene:	Frk / 79209	RGDID:	621423	Length:	506	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	59/150 - (39%)
Similarity:	82/150 - (54%)	Gaps:	15/150 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGK--------EGLIPSNYI----EMK 56
            :|..|:.|...::|||.....|::|:...:..|....|:.|        :|.|||||:    .::
  Rat    49 VALFDYEARTAEDLSFHAGDKLQVLDTSHEGWWLARHLEKKGPGLGQQLQGYIPSNYVAEDRSLQ 113

  Fly    57 NHDWYYGRITRADAEK--LLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFL 119
            ...|::|.|.||||||  |.|....||||||.|||..|||||||.....|:|:::.|..:..|||
  Rat   114 AEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFL 178

  Fly   120 WVVK-FNSLNELVEYHRTAS 138
            ...| |::|||.|.|:.|.|
  Rat   179 TRRKTFSTLNEFVNYYTTTS 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	16/56 (29%)
		SH2_Grb2_like	56..149	CDD:199828	41/85 (48%)
		SH3_GRB2_like_C	156..208	CDD:212739
Frk	NP_077344.1	SH3_Src_like	48..105	CDD:212779	15/55 (27%)
		SH2_Src_Frk	113..208	CDD:199831	41/85 (48%)
		PTKc_Frk_like	226..495	CDD:270653
		Pkinase_Tyr	235..488	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910