DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and Fgr

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_077059.2	Gene:	Fgr / 79113	RGDID:	621319	Length:	517	Species:	Rattus norvegicus

Alignment Length:	145	Identity:	49/145 - (33%)
Similarity:	87/145 - (60%)	Gaps:	15/145 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE--LDGKEGLIPSNYI----EMKNHDWYY 62
            :|.:|:.|...|:|:|.|.:...||| ..:.:|:.|.  ..|:.|.:||||:    .::..:||:
  Rat    71 VALYDYEARTGDDLTFTKGEKFHILN-NTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQAEEWYF 134

  Fly    63 GRITRADAEK-LLSNKH-EGAFLIRISESSPGDFSLSVK-----CPDGVQHFKVLR-DAQSKFFL 119
            |:|:|.|||: |||:.: :||||||.||::.|.:|||::     ..|.::|:|:.: |....:..
  Rat   135 GKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYIT 199

  Fly   120 WVVKFNSLNELVEYH 134
            ...:|.|:.:||.::
  Rat   200 TRAQFESVQDLVRHY 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/50 (34%)
		SH2_Grb2_like	56..149	CDD:199828	31/87 (36%)
		SH3_GRB2_like_C	156..208	CDD:212739
Fgr	NP_077059.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	17..46
		SH3	68..125	CDD:418401	18/54 (33%)
		SH2_Src_Fgr	128..228	CDD:198230	31/87 (36%)
		PKc_like	255..502	CDD:419665
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910