Protein Alignment drk and SRMS

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_543013.1
• Gene: SRMS / 6725
• HGNCID: 11298
• Length: 488
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 50/171 - (29%)
• Similarity: 90/171 - (52%)
• Gaps: 15/171 - (8%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNW-YRAELDGK--EGLIPSNYI------EMKNHD 59
            :|.:||:|....|||.|:..  ::..:|:...: :...|.|:  .||:|..::      .:.:..
Human    57 LALYDFTARCGGELSVRRGD--RLCALEEGGGYIFARRLSGQPSAGLVPITHVAKASPETLSDQP 119

  Fly    60 WYYGRITRADAEKLLSN--KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVV 122
            ||:..::|..|::||.:  ...||||||.||||.|.:||||:....|.|::|...|....:|...
Human   120 WYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSLYLQKG 184

  Fly   123 K-FNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYD 162
            : |..|.||:.|:: |:....|:..|:..:|::...|.:::
Human   185 RLFPGLEELLTYYK-ANWKLIQNPLLQPCMPQKAPRQDVWE 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	14/51 (27%)
		SH2_Grb2_like	56..149	CDD:199828	34/95 (36%)
		SH3_GRB2_like_C	156..208	CDD:212739	1/7 (14%)
SRMS	NP_543013.1	SH3_Srms	55..109	CDD:212780	14/53 (26%)
		SH2	119..197	CDD:472789	30/77 (39%)
		PTKc_Srm_Brk	223..483	CDD:133248	0/2 (0%)