Protein Alignment drk and SRC

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: XP_016883513.1
• Gene: SRC / 6714
• HGNCID: 11283
• Length: 542
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 63/220 - (28%)
• Similarity: 108/220 - (49%)
• Gaps: 43/220 - (19%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNME-----DDSNWYRAE--LDGKEGLIPSNYI----EMKN 57
            :|.:|:.:..:.:|||:|.:.|:|:|..     .:.:|:.|.  ..|:.|.|||||:    .::.
Human    90 VALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQA 154

  Fly    58 HDWYYGRITRADAEKLLSNKH--EGAFLIRISESSPGDFSLSVKCPD-----GVQHFKVLRDAQS 115
            .:||:|:|||.::|:||.|..  .|.||:|.||::.|.:.|||...|     .|:|:|:.:....
Human   155 EEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSG 219

  Fly   116 KFFLWV-VKFNSLNELVEY---------HRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGE 170
            .|::.. .:||||.:||.|         ||..:|..:...:.:.:..:..       .:|:||..
Human   220 GFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAW-------EIPRESLR 277

  Fly   171 LDFRRGDVITVTDRSDENW---WNG 192
            |:.:.|.     ....|.|   |||
Human   278 LEVKLGQ-----GCFGEVWMGTWNG 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/55 (31%)
		SH2_Grb2_like	56..149	CDD:199828	35/109 (32%)
		SH3_GRB2_like_C	156..208	CDD:212739	10/40 (25%)
SRC	XP_016883513.1	SH3_Src	88..149	CDD:212941	18/58 (31%)
		SH2_Src_Src	153..253	CDD:198228	34/99 (34%)
		PTKc_Src	266..542	CDD:270656	10/44 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910