DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and sh3d21

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:XP_005158368.1 Gene:sh3d21 / 641492 ZFINID:ZDB-GENE-051120-57 Length:497 Species:Danio rerio


Alignment Length:252 Identity:54/252 - (21%)
Similarity:94/252 - (37%) Gaps:69/252 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||.:....|.||..|||:.....|:|.::...:..|...:|.||.|:.|.|::  |....|....
Zfish     1 MEVLVLLGFEATMPDELTVHVGDIVKNVSKAKEEGWLEGDLRGKRGMFPGNFV--KEVPVYLIGD 63

  Fly    66 TRADAEKLLSNK------------------HEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRD 112
            :..:...:...|                  ||....:.:.|:                 .::||:
Zfish    64 SNREPRSIRKTKKTTVQTRKCEVVFPYVPTHEDELQLLVGET-----------------IEILRE 111

  Fly   113 AQSKFFLWVVKFNSLNEL----VEYHRTASVSRSQDVKLRDMIPEEML----------------- 156
            .:..:  |:.|.|  |::    ..:.:...|....|.|.|..:...:.                 
Zfish   112 IEDGW--WMGKKN--NQIGAFPSNFVKEIFVPSKDDAKARPKLSGSVFGKEGKLQQRPSLRKKTS 172

  Fly   157 -----VQALYDFVPQESGELDFRRGDVITVTDRS--DENWWNGEIGNRKGIFPATYV 206
                 .|.::|:......||:.::||||||.::|  |:.||.||:..|:|.||..:|
Zfish   173 NVKECCQVMFDYAAVAEDELNLKKGDVITVINKSTEDDGWWEGEVNGRRGFFPDNFV 229

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 16/50 (32%)
SH2_Grb2_like 56..149 CDD:199828 15/114 (13%)
SH3_GRB2_like_C 156..208 CDD:212739 21/75 (28%)
sh3d21XP_005158368.1 SH3_CD2AP-like_1 2..55 CDD:212806 16/54 (30%)
SH3_CD2AP-like_2 83..135 CDD:212807 9/72 (13%)
SH3_D21-like 177..231 CDD:213018 21/53 (40%)

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