Protein Alignment drk and Sh3kbp1

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001361630.1
• Gene: Sh3kbp1 / 58194
• MGIID: 1889583
• Length: 709
• Species: Mus musculus
• Alignment Length: 207
• Identity: 48/207 - (23%)
• Similarity: 85/207 - (41%)
• Gaps: 57/207 - (27%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            :|||.:.|:.|..||||:....:::..:..| |..|:..:::|:.||.|.|::          |.
Mouse     2 VEAIVEFDYQAQHDDELTISVGEVITNIRKE-DGGWWEGQINGRRGLFPDNFV----------RE 55

  Fly    66 TRADAEK-LLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNE 129
            .:.|.:| ||||                      |.|:     |.:.|..|.           |.
Mouse    56 IKKDMKKDLLSN----------------------KAPE-----KPMHDVSSG-----------NA 82

  Fly   130 LVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEI 194
            |:........::..:.:.|       ..|..:.::||...||:.:.||:|.|....:|.||.|.:
Mouse    83 LLSSETILRTNKRGERRRR-------RCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVL 140

  Fly   195 GNRKGIFPATYV 206
            ..:.|:||:.::
Mouse   141 NGKTGMFPSNFI 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/50 (34%)
		SH2_Grb2_like	56..149	CDD:199828	14/93 (15%)
		SH3_GRB2_like_C	156..208	CDD:212739	16/51 (31%)
Sh3kbp1	NP_001361630.1	SH3_CIN85_1	3..55	CDD:212985	17/62 (27%)
		SH3_CIN85_2	102..154	CDD:212988	16/51 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..242
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	289..309
		SH3_CIN85_3	315..370	CDD:212990
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..485
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..650