DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and PTK6

DIOPT Version :9

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_005966.1 Gene:PTK6 / 5753 HGNCID:9617 Length:451 Species:Homo sapiens


Alignment Length:145 Identity:52/145 - (35%)
Similarity:78/145 - (53%) Gaps:13/145 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 DFSATADDELSFRKTQILKILNMEDDSNWYRAELDG-----KEGLIPSNYI----EMKNHDWYYG 63
            ||.:..|:|||||...:..:...|:.. |:...||.     .:|.:|.||:    .:::..|::|
Human    18 DFKSRTDEELSFRAGDVFHVARKEEQW-WWATLLDEAGGAVAQGYVPHNYLAE
RETVESEPWFFG 81

  Fly    64 RITRADAEKLL--SNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFL-WVVKFN 125
            .|:|::|.:.|  .....||||||:||....|:.|||:....|:|:|:.|.|..:..| ..|.|.
Human    82 CISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRRAGGRLHLNEAVSFL 146

  Fly   126 SLNELVEYHRTASVS 140
            ||.|||.|||..|:|
Human   147 SLPELVNYHRAQSLS 161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 15/49 (31%)
SH2_Grb2_like 56..149 CDD:199828 36/88 (41%)
SH3_GRB2_like_C 156..208 CDD:212739
PTK6NP_005966.1 SH3_Brk 12..69 CDD:212781 16/51 (31%)
SH2_PTK6_Brk 75..174 CDD:198221 36/87 (41%)
Linker 171..190
PTKc_Srm_Brk 184..444 CDD:133248
STYKc 192..441 CDD:214568
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000006
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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