DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment drk and frk

DIOPT Version :9

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:XP_021324228.1 Gene:frk / 567549 ZFINID:ZDB-GENE-110411-7 Length:512 Species:Danio rerio


Alignment Length:170 Identity:58/170 - (34%)
Similarity:93/170 - (54%) Gaps:27/170 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDG----KEGLIPSNYI----EMKNHDW 60
            :|.:|::|..||:|||.....|:.:...:|. |:...:.|    |:|.||:||:    .:....|
Zfish    58 VALYDYTARTDDDLSFNAGDKLEPITKGEDW-WFSKAITGISANKKGYIPANY
VAPVESLDAEPW 121

  Fly    61 YYGRITRADAEKLL---SNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVV 122
            |:....|:||||:|   .|| :||||||..||.||:.||||:....|:|:|:.:.....::|...
Zfish   122 YFPETKRSDAEKMLISQENK-KGAFLIRNCESQPGELSLSVRDDVKVKHYKIRKLDNGGYYLSTA 185

  Fly   123 K-FNSLNELVEYHRTASVSRSQD---VKL-----RDMIPE 153
            : |.:|.||||::     |:.:|   |:|     :.:.||
Zfish   186 RNFPTLRELVEHY-----SKHEDGLCVRLAEPCKKSVAPE 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 17/52 (33%)
SH2_Grb2_like 56..149 CDD:199828 38/104 (37%)
SH3_GRB2_like_C 156..208 CDD:212739
frkXP_021324228.1 SH3_Src_like 56..109 CDD:212779 16/51 (31%)
SH2_Src_family 117..212 CDD:199827 38/100 (38%)
PTKc_Frk_like 230..500 CDD:270653
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000006
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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