DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and fes

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:XP_005166438.1 Gene:fes / 566739 ZFINID:ZDB-GENE-100812-10 Length:835 Species:Danio rerio


Alignment Length:132 Identity:39/132 - (29%)
Similarity:67/132 - (50%) Gaps:13/132 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 WYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKF 124
            ||:|.|.|.:.::||  |::|.||:|.|:... ::.|||......:|| :::.....:.|....|
Zfish   473 WYHGAIPRMEVQELL--KNDGDFLVRESQGKQ-EYVLSVHWGGQCRHF-LIQSTDGVYRLDGEGF 533

  Fly   125 NS----LNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFV-PQESGELDFRRGDVITVTDR 184
            .|    :|.|...|:|  |::..::.|:..||::..|....|.: .|..|..:|  |:|.:...|
Zfish   534 ISVPLLVNHLFNSHQT--VTKRTEIVLKKPIPKDKWVLEHDDVILGQSIGRGNF--GEVFSGRLR 594

  Fly   185 SD 186
            ||
Zfish   595 SD 596

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738
SH2_Grb2_like 56..149 CDD:199828 27/92 (29%)
SH3_GRB2_like_C 156..208 CDD:212739 10/32 (31%)
fesXP_005166438.1 F-BAR_Fes 7..243 CDD:153369
SH2_Fps_family 466..550 CDD:198224 25/82 (30%)
Protein Kinases, catalytic domain 577..831 CDD:473864 8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

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