DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and grapb

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001025251.2	Gene:	grapb / 555184	ZFINID:	ZDB-GENE-050913-4	Length:	214	Species:	Danio rerio

Alignment Length:	216	Identity:	105/216 - (48%)
Similarity:	137/216 - (63%)	Gaps:	8/216 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            |||.|.:.|.||..|||||:|.:|||:.||:||.|||.|||.|:.|.:|.|||.::.|.|:.|.|
Zfish     1 MEAEALYSFRATECDELSFQKGEILKVTNMDDDPNWYTAELLGRRGYVPKNYINVRPHTWFVGGI 65

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|..||..|.....||||||.|||:||:||:||...|.|||||||:|...::|:|...|:|||:|
Zfish    66 SRQAAENRLRPLECGAFLIRESESTPGEFSVSVSYGDHVQHFKVLKDGLGQYFIWDEVFSSLNQL 130

  Fly   131 VEYHRTASVSRSQDVKLRDMIPEEMLVQ-----ALYDFVPQESGELDFRRGDVITVTDRSDENWW 190
            |:::|..|:::.:.|.||:  ||..|.:     |::||.......|.|.|||||.:.|.||...|
Zfish   131 VDFYRINSIAKERTVFLRE--PEGSLARPRHAHAIFDFTSNHVTHLRFLRGDVIDLLDCSDAQCW 193

  Fly   191 NGEIGNRKGIFPATYVTP-YH 210
            .|....|.||||..||.| ||
Zfish   194 RGRCRGRVGIFPPEYVQPIYH 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	29/50 (58%)
		SH2_Grb2_like	56..149	CDD:199828	44/92 (48%)
		SH3_GRB2_like_C	156..208	CDD:212739	23/56 (41%)
grapb	NP_001025251.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46063
OrthoDB	1	1.010	-	-		D1091250at2759
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X588
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.030