Protein Alignment drk and grap2a

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001017756.1
• Gene: grap2a / 550452
• ZFINID: ZDB-GENE-050417-275
• Length: 284
• Species: Danio rerio
• Alignment Length: 282
• Identity: 102/282 - (36%)
• Similarity: 142/282 - (50%)
• Gaps: 79/282 - (28%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            |||..|:|||.||:|||||||...||||..:||  |::|||.|.||.:|.||::.:...|:....
Zfish     1 MEARGKYDFSGTAEDELSFRKGDTLKILGSQDD--WFKAELHGHEGYVPKNYVDRQIPSWFKESA 63

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|..||:.|.::..||||||.|:|||||||:||:....||||||::|....::||..||.|||:|
Zfish    64 SRGSAEETLMSREVGAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYYLWTEKFTSLNKL 128

  Fly   131 VEYHRTASVSRSQDVKLRDMIPEE----------------------------------------- 154
            |::::|.|:|:.:::.|||...:|
Zfish   129 VDFYKTTSISKQKEIFLRDGSGDEPRAPPPIKSQPEVRPPPGGGYGSPQTSSQNRSTTDPTHNQK 193

  Fly   155 ------------------------------------MLVQALYDFVPQESGELDFRRGDVITVTD 183
                                                :.|:|:|||..:|..||.|..||:|.|.|
Zfish   194 GKRGSVEEKSNTLGHQGKNSPAPRRTSETAPAPRSTIQVRAIYDFTAEEDDELGFNSGDIIEVLD 258

  Fly   184 RSDENWWNGEIGNRKGIFPATY 205
            |||.:||.|.:..|.|:|||.|
Zfish   259 RSDASWWKGRLRGRSGLFPANY 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	30/50 (60%)
		SH2_Grb2_like	56..149	CDD:199828	41/92 (45%)
		SH3_GRB2_like_C	156..208	CDD:212739	26/50 (52%)
grap2a	NP_001017756.1	SH3_GRAP2_N	2..53	CDD:212880	31/52 (60%)
		SH2_Grb2_like	54..147	CDD:199828	41/92 (45%)
		SH3_GRAP2_C	231..283	CDD:212883	26/50 (52%)