DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and Sla2

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001165589.1	Gene:	Sla2 / 499931	RGDID:	1562071	Length:	263	Species:	Rattus norvegicus

Alignment Length:	146	Identity:	47/146 - (32%)
Similarity:	81/146 - (55%)	Gaps:	16/146 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWY--RAELDGKEGLIPSNYIEMKNHDWYYG 63
            :.|:|...|.|.....||.|..:.|.|::  :|.:|:  ::|:.|:|..|||.|:...:|.|.|.
  Rat    37 VSAVALGSFPAGEQARLSLRVGEPLTIIS--EDGDWWTVQSEVSGREYHIPSVYVAKVSHGWLYE 99

  Fly    64 RITRADAEK--LLSNKHEGAFLIRISESSPGDFSLSVKCP-----DGVQHFKVLRDAQSKFFLWV 121
            .::|..||:  ||.....||||||.|::..|.:|||::..     |.::|:::.|  ....:|::
  Rat   100 GLSREKAEELLLLPGNPGGAFLIRESQTRRGCYSLSIRLSRPASWDRIRHYRIQR--LDNGWLYI 162

  Fly   122 ---VKFNSLNELVEYH 134
               :.|.||:.|||::
  Rat   163 SPRLTFPSLHALVEHY 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/52 (33%)
		SH2_Grb2_like	56..149	CDD:199828	29/89 (33%)
		SH3_GRB2_like_C	156..208	CDD:212739
Sla2	NP_001165589.1	SH3	39..92	CDD:302595	18/54 (33%)
Sla2	NP_001165589.1	SH2_SLAP	85..187	CDD:198207	32/96 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910