Protein Alignment drk and grb2a

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001007770.1
• Gene: grb2a / 493609
• ZFINID: ZDB-GENE-041121-1
• Length: 217
• Species: Danio rerio
• Alignment Length: 212
• Identity: 139/212 - (65%)
• Similarity: 166/212 - (78%)
• Gaps: 4/212 - (1%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||||||:||.|||||||||::.:|||:||.|.|.|||:|||:||||.||.||||||.|.|:||:|
Zfish     1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKI 65

  Fly    66 TRADAEKLLS-NKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNE 129
            .||.||::|: .:|:||||||.|||:|||||||||..:.|||||||||...|:|||||||||||.
Zfish    66 PRAKAEEMLNKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNS 130

  Fly   130 LVEYHRTASVSRSQDVKLRDM--IPE-EMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWN 191
            ||:|||:.||||:|.:.|||:  :|: ...||||:||.|||.|||.|||||.|.|.|.||.|||.
Zfish   131 LVDYHRSTSVSRNQPIFLRDIEQVPQNSTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWK 195

  Fly   192 GEIGNRKGIFPATYVTP 208
            |....:.|:||..||||
Zfish   196 GACHGQTGMFPRNYVTP 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	36/50 (72%)
		SH2_Grb2_like	56..149	CDD:199828	62/93 (67%)
		SH3_GRB2_like_C	156..208	CDD:212739	31/51 (61%)
grb2a	NP_001007770.1	SH3_GRB2_N	1..56	CDD:212879	40/54 (74%)
		SH2_Grb2_like	56..150	CDD:199828	62/93 (67%)
		SH3_GRB2_C	160..212	CDD:212882	31/51 (61%)