DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and Shark

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_524743.2 Gene:Shark / 44353 FlyBaseID:FBgn0015295 Length:939 Species:Drosophila melanogaster


Alignment Length:116 Identity:34/116 - (29%)
Similarity:60/116 - (51%) Gaps:17/116 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 WYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCPDGVQHFKVLR-DAQSKFF---- 118
            ||:|.::|..|::||...:| |.||:|.|.::.|||.||:.|...|.|::|.| ..:..||    
  Fly    10 WYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRRHGGEDAFFSIDD 74

  Fly   119 -LWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQES 168
             :.....:.|:.||:|::.|:          :.:|.::.|..:.|..|..:
  Fly    75 KVQTKILHGLDTLVDYYQQAA----------NGLPTKLTVPLIRDLPPHNT 115

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738
SH2_Grb2_like 56..149 CDD:199828 30/95 (32%)
SH3_GRB2_like_C 156..208 CDD:212739 3/13 (23%)
SharkNP_524743.2 SH2_Nterm_shark_like 8..91 CDD:198210 28/80 (35%)
ANKYR <94..317 CDD:440430 5/32 (16%)
ANK repeat 124..151 CDD:293786
ANK repeat 153..184 CDD:293786
ANK repeat 186..217 CDD:293786
ANK repeat 220..245 CDD:293786
SH2_Cterm_shark_like 287..395 CDD:198211
PTKc_Syk_like 666..926 CDD:270650
Blue background indicates that the domain is not in the aligned region.

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