DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment drk and Crk

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_651908.1 Gene:Crk / 43775 FlyBaseID:FBgn0024811 Length:271 Species:Drosophila melanogaster


Alignment Length:166 Identity:46/166 - (27%)
Similarity:85/166 - (51%) Gaps:25/166 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 HDWYYGRITRADAEKLLSNKHE-GAFLIRISESSPGDFSLSVKCPDGVQHF---KVLRDAQSKFF 118
            :.||:|.::|.||.::|.|:.| |.||:|.|.|..||:.|.|:....|.::   ||.:..|..:.
  Fly    10 NSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQIVYR 74

  Fly   119 LWVVKFNSLNELVEYHR-----TASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGELDFRRGDV 178
            :....|::|.:|:.::.     |..:.|....::..:|.:       :|||..:..:|.|:||:|
  Fly    75 IGDQSFDNLPKLLTFYTLHYLDTTPLKRPACRRVEKVIGK-------FDFVGSDQDDLPFQRGEV 132

  Fly   179 ITVTDRSDENWW-----NGEIGNRKGIFPATYVTPY 209
            :|:..:.::.||     :|:||.    .|..|:..|
  Fly   133 LTIVRKDEDQWWTARNSSGKIGQ----IPVPYIQQY 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738
SH2_Grb2_like 56..149 CDD:199828 28/99 (28%)
SH3_GRB2_like_C 156..208 CDD:212739 16/56 (29%)
CrkNP_651908.1 SH2_CRK_like 4..108 CDD:198180 28/97 (29%)
SH3_CRK_N 109..163 CDD:212692 17/64 (27%)
SH3_CRK_C 201..257 CDD:212693
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.