Protein Alignment drk and lck

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001001596.1
• Gene: lck / 414333
• ZFINID: ZDB-GENE-040617-1
• Length: 503
• Species: Danio rerio
• Alignment Length: 222
• Identity: 75/222 - (33%)
• Similarity: 113/222 - (50%)
• Gaps: 29/222 - (13%)

  Fly     3 AIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE--LDGKEGLIPSNYI----EMKNHDWY 61
            ||.|:|  ....|:|.|.|.:.:|||:. ||..||.||  ..|:.|.||.|::    .|:...|:
Zfish    60 AIYKYD--PAHSDDLGFEKGEKMKILDC-DDPEWYMAESLFTGQRGYIPKNFVAKLNSMETEPWF 121

  Fly    62 YGRITRADA--EKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQ-----HFKVLR-DAQSKFF 118
            |..::|.||  :.|.....:|:||||.||:.||.||:||:..|.:|     |:::.. ||...:.
Zfish   122 YKNLSRNDAMRQLLAPGNTQGSFLIRESETQPGSFSISVRDLDPMQGDIIKHYRIRNMDAGGFYI 186

  Fly   119 LWVVKFNSLNELVE-YHRTASVSRSQDVK-LRDMIPEEMLVQALYDFVPQESGELDFRRGDVITV 181
            ...:.||||:|||: |.|.|....::.|| .:...|::...|..:: ||:||.:|:.|.|.
Zfish   187 TNKISFNSLSELVKHYSREADGLCTRLVKPCQTRAPQKPWWQDEWE-VPRESLKLERRLGQ---- 246

  Fly   182 TDRSDENWWNGEIGNR----KGIFPAT 204
             .:..|.|......||    |.:.|.|
Zfish   247 -GQFGEVWMGLYNNNRQVAIKSLKPGT 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	22/51 (43%)
		SH2_Grb2_like	56..149	CDD:199828	36/102 (35%)
		SH3_GRB2_like_C	156..208	CDD:212739	15/53 (28%)
lck	NP_001001596.1	SH3_Lck	57..111	CDD:212938	22/53 (42%)
		SH2_Src_Lck	116..216	CDD:198225	35/99 (35%)
		PTKc_Lck_Blk	230..493	CDD:270652	14/49 (29%)
		Pkinase_Tyr	238..487	CDD:285015	10/40 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910