Protein Alignment drk and grb2b

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_998200.1
• Gene: grb2b / 406308
• ZFINID: ZDB-GENE-040426-1975
• Length: 217
• Species: Danio rerio
• Alignment Length: 212
• Identity: 140/212 - (66%)
• Similarity: 167/212 - (78%)
• Gaps: 4/212 - (1%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||||||:||.|||||||||::.:|||:||.|.|.|||:|||:||:|.||.||||||.|.|::|||
Zfish     1 MEAIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKAHPWFFGRI 65

  Fly    66 TRADAEKLLS-NKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNE 129
            .||.||::|: .:|:||||||.|||:|||||||||..:.|||||||||...|:||||||||||||
Zfish    66 PRARAEEILNKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNE 130

  Fly   130 LVEYHRTASVSRSQDVKLRDM--IPEE-MLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWN 191
            ||:||||.||||:|.:.|||:  :|:. ..||||:||.|||.|||.|||||.|.|.|.||.|||.
Zfish   131 LVDYHRTTSVSRNQQIFLRDIEQVPQHPTYVQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWK 195

  Fly   192 GEIGNRKGIFPATYVTP 208
            |....:.|:||..||||
Zfish   196 GACHGQTGMFPRNYVTP 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	35/50 (70%)
		SH2_Grb2_like	56..149	CDD:199828	64/93 (69%)
		SH3_GRB2_like_C	156..208	CDD:212739	31/51 (61%)
grb2b	NP_998200.1	SH3_GRB2_N	1..56	CDD:212879	39/54 (72%)
		SH2_Grb2_like	56..150	CDD:199828	64/93 (69%)
		SH3_GRB2_C	160..212	CDD:212882	31/51 (61%)