Protein Alignment drk and grap2b

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_956972.1
• Gene: grap2b / 393651
• ZFINID: ZDB-GENE-040426-1485
• Length: 249
• Species: Danio rerio
• Alignment Length: 250
• Identity: 102/250 - (40%)
• Similarity: 139/250 - (55%)
• Gaps: 44/250 - (17%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            |||..|:||||||.|||||||..::|||...||  |:|||::|.||.:|.|||......||....
Zfish     1 MEATGKYDFSATAGDELSFRKGDVIKILGTNDD--WFRAEINGMEGFVPRNYIVTTFPSWYKENT 63

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|..|:..|..:..|||:||.|:|||||||:||:..:.||||||:||.|.:::||...|.|||:|
Zfish    64 SRQSAQDELMCQPIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQGRYYLWSEMFTSLNKL 128

  Fly   131 VEYHRTASVSRSQDVKL----------------------------RDMIP--------------E 153
            |:|:...|:|:...|.|                            |.:.|              .
Zfish   129 VDYYTHNSISKQSRVFLLTDQRSSSDFLHRKPTEAPPFRQERQDYRSLAPPVARPSQPSLPPQVS 193

  Fly   154 EMLVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTP 208
            .:.|:|:|||..:::.||:|:.||||.|.|:||.:||.|.:..|.|:||..|..|
Zfish   194 ALHVRAMYDFTAEDADELNFQAGDVIEVLDQSDRSWWKGVLRGRTGLFPVNYTNP 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	30/50 (60%)
		SH2_Grb2_like	56..149	CDD:199828	42/120 (35%)
		SH3_GRB2_like_C	156..208	CDD:212739	24/51 (47%)
grap2b	NP_956972.1	SH3	2..51	CDD:473055	30/50 (60%)
		SH2_Grb2_like	54..147	CDD:199828	42/92 (46%)
		SH3	197..248	CDD:473055	24/50 (48%)