Protein Alignment drk and Grap2

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001030116.1
• Gene: Grap2 / 366962
• RGDID: 1307605
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 104/325 - (32%)
• Similarity: 144/325 - (44%)
• Gaps: 119/325 - (36%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||||||.||.|:.:|||||....|||||:.:::  |.:|||..:||.:|.|:|::|..:|::..:
  Rat     1 MEAIAKFDFMASGEDELSFHTGDILKILSNQEE--WLKAELGSQEGYVPKNFIDIKFPEWFHEGL 63

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|..||.||..|..|.|:||.|:|||||||:||:..|.||||||:||.:..:|||..||.|||:|
  Rat    64 SRHQAENLLMGKEIGFFVIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKL 128

  Fly   131 VEYHRTASVSRSQDVKLRD---------------------------------------------- 149
            |:|:||.|:|:.:.:.|||
  Rat   129 VDYYRTTSISKQKQIFLRDGTQDQQGHRGNSLDRRTQGGPPREVPSGTAGEEIRPLMNRKLSDHL 193

  Fly   150 ------MIPEEML---------------------------------------------------- 156
                  ..|.:.|
  Rat   194 PLGTQQFHPHQQLPPQFPPGPQPPPQQRYLQHFHQDRRGGSLDINDGHLGIGSEMNATLMHRRHT 258

  Fly   157 -------------VQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTP 208
                         .:|||||...|..||..|.|:|:.|.|.|:.:||.|.:.|:.|:|||.||.|
  Rat   259 DPVQLQAAGRVRWARALYDFEALEEDELGLRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAP 323

  Fly   209  208
              Rat   324  323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	26/50 (52%)
		SH2_Grb2_like	56..149	CDD:199828	47/92 (51%)
		SH3_GRB2_like_C	156..208	CDD:212739	25/116 (22%)
Grap2	NP_001030116.1	SH3	2..53	CDD:473055	27/52 (52%)
		SH2_Grb2_like	54..147	CDD:199828	47/92 (51%)
		SH3_GRAP2_C	271..323	CDD:212883	24/51 (47%)