DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and Ptk6

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_001102438.1 Gene:Ptk6 / 366275 RGDID:1309098 Length:451 Species:Rattus norvegicus


Alignment Length:146 Identity:53/146 - (36%)
Similarity:87/146 - (59%) Gaps:15/146 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 DFSATADDELSFRKTQILKILNMEDDSNWYRAEL---DGK---EGLIPSNYIEMK----NHDWYY 62
            ||.|..|:||||:...:|.:...|:  .|:.|.|   :||   ||.:|.||:..|    :..|::
  Rat    18 DFKARTDEELSFQAGDLLHVTRKEE--QWWWATLLDAEGKALAEGYVPHNYLAEKETVESEPWFF 80

  Fly    63 GRITRADAEKLLSNKH--EGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFL-WVVKF 124
            |.|:|::|...|.::.  :|.||||:|:....|:.|||...:.|:|:::.|::..:..| .||.|
  Rat    81 GCISRSEAMHRLQSEDYPKGTFLIRVSQKPGADYVLSVWDAEAVRHYRIWRNSAGRLHLNEVVSF 145

  Fly   125 NSLNELVEYHRTASVS 140
            :||:|||.||:|.::|
  Rat   146 SSLSELVNYHKTHNLS 161

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 19/50 (38%)
SH2_Grb2_like 56..149 CDD:199828 33/92 (36%)
SH3_GRB2_like_C 156..208 CDD:212739
Ptk6NP_001102438.1 SH3_Brk 12..69 CDD:212781 20/52 (38%)
SH2_PTK6_Brk 75..174 CDD:198221 32/87 (37%)
Protein Kinases, catalytic domain 184..444 CDD:473864
Blue background indicates that the domain is not in the aligned region.

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