DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and dock

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_722657.1 Gene:dock / 33262 FlyBaseID:FBgn0010583 Length:548 Species:Drosophila melanogaster


Alignment Length:230 Identity:62/230 - (26%)
Similarity:105/230 - (45%) Gaps:76/230 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNM-EDDSNWYRAELD-GKEGLIPSNYIEMKN--------- 57
            :|.:.|::..|.||||.|...|:|::. ..|.:||:|..: |:.||:|.||::..|         
  Fly   330 VALYSFTSNNDQELSFEKGDRLEIVDRPASDPDWYKARNNQGQVGLVPRNYLQELNDYLATPYRN 394

  Fly    58 ---------------------------------------------------HDWYYGRITRADAE 71
                                                               ..||||.|||:..:
  Fly   395 ASASAGNGNGGGSNGGAGGGGGNDSMERRNEGNKPAAQSSGQPIERPNLAGKSWYYGAITRSQCD 459

  Fly    72 KLLS-NKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNELVEYHR 135
            .:|: :.|:|.||||.||::.||:|:|:|.|...:||:| ...|:.:.:...||:||::||::::
  Fly   460 TVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNKHFRV-HVEQNMYCIGQRKFHSLDQLVDHYQ 523

  Fly   136 TASV-SRSQDVKLRDMIPEEMLVQALYDFVPQESG 169
            .|.: :..|..||       .||::|    |:.:|
  Fly   524 RAPIYTNKQGEKL-------YLVRSL----PKANG 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 19/50 (38%)
SH2_Grb2_like 56..149 CDD:199828 37/154 (24%)
SH3_GRB2_like_C 156..208 CDD:212739 5/14 (36%)
dockNP_722657.1 SH3_Nck_1 154..204 CDD:212699
SH3_Nck_2 256..308 CDD:212700
SH3_Nck_3 328..383 CDD:212701 20/52 (38%)
SH2_Nck_family 446..538 CDD:198196 36/99 (36%)
Blue background indicates that the domain is not in the aligned region.

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