Protein Alignment drk and src

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: XP_017209008.1
• Gene: src / 325084
• ZFINID: ZDB-GENE-030131-3809
• Length: 549
• Species: Danio rerio
• Alignment Length: 225
• Identity: 66/225 - (29%)
• Similarity: 112/225 - (49%)
• Gaps: 44/225 - (19%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILN-----MEDDSNWY--RAELDGKEGLIPSNY------IEM 55
            :|.:|:.:....:|||||.:.|:|:|     ...:.:|:  |:...|:.|.|||||      |:.
Zfish    88 VALYDYESRTASDLSFRKGERLQIVNNTRKLNPREGDWWLARSLTTGESGYIPSNYVAPSDSIQA 152

  Fly    56 KNH-------DWYYGRITRADAEKLLSN--KHEGAFLIRISESSPGDFSLSVKCPD-----GVQH 106
            ::|       .||:|:|||.|:|:||.|  ...|.||:|.||::.|.:.|||...|     .|:|
Zfish   153 EDHLRLTLEKRWYFGKITRRDSERLLLNLENRRGTFLVRESETTKGAYCLSVLDYDNVKGLNVKH 217

  Fly   107 FKVLRDAQSKFFLWV-VKFNSLNELVEYHRTASVSRSQDVKLRDMI-----PEEMLVQALYDFVP 165
            :|:.:.....|::.. .:|::|.:||.::|..:.....  .|.|:.     |.:.|.:..:: :|
Zfish   218 YKIRKLDSGGFYITSRTQFSTLQQLVNHYRQHADGLCH--SLTDVCPVLKPPTQGLARDAWE-IP 279

  Fly   166 QESGELDFRRGDVITVTDRSDENW---WNG 192
            ::|..||.:.|.     ....|.|   |||
Zfish   280 RDSLRLDVKLGQ-----GCFGEVWMGTWNG 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	19/61 (31%)
		SH2_Grb2_like	56..149	CDD:199828	33/107 (31%)
		SH3_GRB2_like_C	156..208	CDD:212739	11/40 (28%)
src	XP_017209008.1	SH3	85..148	CDD:473055	19/59 (32%)
		SH2_Src_Src	162..260	CDD:198228	32/99 (32%)
		PTKc_Src	273..549	CDD:270656	10/38 (26%)