DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and Abl1

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_001094320.1 Gene:Abl1 / 311860 RGDID:1584969 Length:1143 Species:Rattus norvegicus


Alignment Length:140 Identity:51/140 - (36%)
Similarity:83/140 - (59%) Gaps:5/140 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYI----EMKNHDWYYGR 64
            :|.:||.|:.|:.||..|.:.|::|....:..|..|:....:|.:|||||    .::.|.||:|.
  Rat    86 VALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGP 150

  Fly    65 ITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFL-WVVKFNSLN 128
            ::|..||.|||:...|:||:|.||||||..|:|::....|.|:::...:..|.:: ...:||:|.
  Rat   151 VSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLA 215

  Fly   129 ELVEYHRTAS 138
            |||.:|.|.:
  Rat   216 ELVHHHSTVA 225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 16/48 (33%)
SH2_Grb2_like 56..149 CDD:199828 33/84 (39%)
SH3_GRB2_like_C 156..208 CDD:212739
Abl1NP_001094320.1 SH3_Abl 84..137 CDD:212784 18/50 (36%)
SH2_ABL 142..235 CDD:198189 33/84 (39%)
PTKc_Abl 254..516 CDD:270645
FABD 1019..1143 CDD:197885
Blue background indicates that the domain is not in the aligned region.

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