DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and Srms

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001011961.1	Gene:	Srms / 296472	RGDID:	1306602	Length:	507	Species:	Rattus norvegicus

Alignment Length:	165	Identity:	52/165 - (31%)
Similarity:	82/165 - (49%)	Gaps:	13/165 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDG--KEGLIPSNYIEM------KNHDWY 61
            |.:||:|...:|||..:...|..|. |:....:...|.|  ..||:|..|:..      .:..||
  Rat    73 ALYDFTARCAEELSVSRGDRLYALK-EEGEYIFAQRLSGPPSTGLVPVTYLAKATPETPSDQPWY 136

  Fly    62 YGRITRADAEKLLSN--KHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVK- 123
            :..|:|..|::||.:  ...||||||.||||.|.:||||:....|.|:::........:|...:
  Rat   137 FNGISRTQAQQLLLSPANAPGAFLIRPSESSIGGYSLSVRAQAKVCHYRICMAPSGGLYLQEGRL 201

  Fly   124 FNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQ 158
            |.||:.|:.|::| :....|:..|:..:|:..|.|
  Rat   202 FPSLDALLAYYKT-NWKLIQNPLLQPCVPQMPLAQ 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	15/49 (31%)
		SH2_Grb2_like	56..149	CDD:199828	33/95 (35%)
		SH3_GRB2_like_C	156..208	CDD:212739	2/3 (67%)
Srms	NP_001011961.1	SH3	70..124	CDD:302595	16/51 (31%)
		SH2	134..212	CDD:301589	29/77 (38%)
		PTKc_Srm_Brk	238..498	CDD:133248
		Pkinase_Tyr	245..495	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910