Protein Alignment drk and csk-1

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001293162.1
• Gene: csk-1 / 266817
• WormBaseID: WBGene00000812
• Length: 624
• Species: Caenorhabditis elegans
• Alignment Length: 210
• Identity: 49/210 - (23%)
• Similarity: 86/210 - (40%)
• Gaps: 54/210 - (25%)

  Fly    19 FRKTQILKILNMEDDSNWYRA-ELDGKEGLI---------------------------------- 48
            |||...::||....|..|||| ..:.:|||:
 Worm   155 FRKDDHVRILGNTTDPAWYRARNANQEEGLVHADCVVRINGQAYDNGIVRMRASGCDVAPGAAST 219

  Fly    49 ----PSNYIEMKNHD-WYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFK 108
                .|::....||. |::..|:|.:.||||..|.:|.||:|.|.:.||||:|.:.....|:|::
 Worm   220 TSSTSSHHSTAANHQPWFHSMISRENTEKLLRGKPDGTFLVRESTNFPGDFTLCMSFHGKVEHYR 284

  Fly   109 VLRDAQSKFFLWVVK---FNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGE 170
            :.:.:..:  |...|   |::|.:||.:::     |..|.....::...:...|.:    ..:|.
 Worm   285 IEQTSGGQ--LTCDKEEYFSNLTQLVSHYK-----RDADGLCHRLVTPIICETATF----SSNGS 338

  Fly   171 LDFRRGDVITVTDRS 185
            ..|.....:.:.||:
 Worm   339 SSFGSSSTVDLEDRT 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	14/72 (19%)
		SH2_Grb2_like	56..149	CDD:199828	30/96 (31%)
		SH3_GRB2_like_C	156..208	CDD:212739	5/30 (17%)
csk-1	NP_001293162.1	SH2_csk_like	232..330	CDD:198190	30/104 (29%)
		PTKc_Csk_like	362..620	CDD:270635