DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and skb5

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_588016.1	Gene:	skb5 / 2539237	PomBaseID:	SPCC24B10.13	Length:	140	Species:	Schizosaccharomyces pombe

Alignment Length:	165	Identity:	35/165 - (21%)
Similarity:	62/165 - (37%)	Gaps:	44/165 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LIPSNYIEMKNHDWYYG---RITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFK 108
            ::..:|:...:|:.:||   |:...:.|:.:.:..:..  |..|:.|           :.:...:
pombe    11 VVGRDYLYPPDHELHYGFHARVIEEEEERFVDDTFDET--IEGSDDS-----------ESIDDTE 62

  Fly   109 VLRDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGELDF 173
            |..||:              |....|.:||.:     .|.|.:       |||||.|....||.|
pombe    63 VFYDAE--------------ESESTHPSASFN-----VLADAV-------ALYDFEPLHDNELGF 101

  Fly   174 RRGDVITVTDRSDENWW--NGEIGNRKGIFPATYV 206
            ..|..:.:...|.:.|.  ..:...|.|:.|.|:|
pombe   102 TTGQRLCILSESSDGWLIAYDDASGRSGLVPETFV 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	0/5 (0%)
		SH2_Grb2_like	56..149	CDD:199828	16/95 (17%)
		SH3_GRB2_like_C	156..208	CDD:212739	17/53 (32%)
skb5	NP_588016.1	SH3_Nbp2-like	84..138	CDD:212799	18/60 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000