Protein Alignment drk and Yes1

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001385513.1
• Gene: Yes1 / 24884
• RGDID: 3977
• Length: 541
• Species: Rattus norvegicus
• Alignment Length: 211
• Identity: 61/211 - (28%)
• Similarity: 111/211 - (52%)
• Gaps: 31/211 - (14%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE--LDGKEGLIPSNYI----EMKNHDWYY 62
            :|.:|:.|...::|||:|.:..:|:| ..:.:|:.|.  ..||.|.|||||:    .::..:||:
  Rat    95 VALYDYEARTTEDLSFKKGERFQIIN-NTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYF 158

  Fly    63 GRITRADAEKLLSN--KHEGAFLIRISESSPGDFSLSVK-----CPDGVQHFKVLRDAQSKFFLW 120
            |::.|.|||:||.|  ...|.||:|.||::.|.:|||::     ..|.|:|:|:.:.....:::.
  Rat   159 GKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYIT 223

  Fly   121 V-VKFNSLNELVEYHRTASVSRSQDVKLRDMIP-----EEMLVQALYDFVPQESGELDFRRGDVI 179
            . .:|::|.:||:::...:.....  ||..:.|     .:.|.:..:: :|:||..|:.:.|.
  Rat   224 TRAQFDTLQKLVKHYTEHADGLCH--KLTTVCPTVKPQTQGLAKDAWE-IPRESLRLEVKLGQ-- 283

  Fly   180 TVTDRSDENW---WNG 192
               ....|.|   |||
  Rat   284 ---GCFGEVWMGTWNG 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	18/50 (36%)
		SH2_Grb2_like	56..149	CDD:199828	30/100 (30%)
		SH3_GRB2_like_C	156..208	CDD:212739	11/40 (28%)
Yes1	NP_001385513.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		SH3_Yes	92..149	CDD:212940	19/54 (35%)
		SH2_Src_family	152..251	CDD:199827	30/100 (30%)
		PTKc_Yes	262..540	CDD:270654	11/41 (27%)