Protein Alignment drk and Yes1

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001192061.1
• Gene: Yes1 / 22612
• MGIID: 99147
• Length: 541
• Species: Mus musculus
• Alignment Length: 211
• Identity: 61/211 - (28%)
• Similarity: 111/211 - (52%)
• Gaps: 31/211 - (14%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE--LDGKEGLIPSNYI----EMKNHDWYY 62
            :|.:|:.|...::|||:|.:..:|:| ..:.:|:.|.  ..||.|.|||||:    .::..:||:
Mouse    95 VALYDYEARTTEDLSFKKGERFQIIN-NTEGDWWEARSIATGKSGYIPSNYVVPADSIQAEEWYF 158

  Fly    63 GRITRADAEKLLSN--KHEGAFLIRISESSPGDFSLSVK-----CPDGVQHFKVLRDAQSKFFLW 120
            |::.|.|||:||.|  ...|.||:|.||::.|.:|||::     ..|.|:|:|:.:.....:::.
Mouse   159 GKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYIT 223

  Fly   121 V-VKFNSLNELVEYHRTASVSRSQDVKLRDMIP-----EEMLVQALYDFVPQESGELDFRRGDVI 179
            . .:|::|.:||:::...:.....  ||..:.|     .:.|.:..:: :|:||..|:.:.|.
Mouse   224 TRAQFDTLQKLVKHYTEHADGLCH--KLTTVCPTVKPQTQGLAKDAWE-IPRESLRLEVKLGQ-- 283

  Fly   180 TVTDRSDENW---WNG 192
               ....|.|   |||
Mouse   284 ---GCFGEVWMGTWNG 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	18/50 (36%)
		SH2_Grb2_like	56..149	CDD:199828	30/100 (30%)
		SH3_GRB2_like_C	156..208	CDD:212739	11/40 (28%)
Yes1	NP_001192061.1	SH3_Yes	92..149	CDD:212940	19/54 (35%)
		SH2_Src_family	152..251	CDD:199827	30/100 (30%)
		PTKc_Yes	262..540	CDD:270654	11/41 (27%)
		Pkinase_Tyr	275..524	CDD:285015	7/27 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910