DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and Txk

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:XP_036020891.1 Gene:Txk / 22165 MGIID:102960 Length:543 Species:Mus musculus


Alignment Length:148 Identity:42/148 - (28%)
Similarity:74/148 - (50%) Gaps:21/148 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 AKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYI------EMKNHDWYYG 63
            |.:||.......|:.::.:...||...|...|...:..|.||||||||:      .::.::||:.
Mouse   118 ALYDFLPREPGNLALKRAEEYLILERCDPHWWKARDRFGNEGLIPSNYVTENRLANLEIYEWYHK 182

  Fly    64 RITRADAEKLLSNK-HEGAFLIRISESSPGDFSLSV------KCPDGVQHFKVLRDAQSKFFLWV 121
            .|||...|:||..: .||||::|.|... |.:::||      .....::|:::.::...:   |.
Mouse   183 NITRNQTERLLRQEAKEGAFIVRDSRHL-GSYTISVFTRARRHTQSSIKHYQIKKNDSGQ---WY 243

  Fly   122 VK----FNSLNELVEYHR 135
            :.    |.|:.||::||:
Mouse   244 ITERHLFPSVPELIQYHQ 261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 16/47 (34%)
SH2_Grb2_like 56..149 CDD:199828 25/91 (27%)
SH3_GRB2_like_C 156..208 CDD:212739
TxkXP_036020891.1 SH3_TXK 114..168 CDD:212840 17/49 (35%)
SH2_Tec_Txk 172..277 CDD:198261 25/94 (27%)
Protein Kinases, catalytic domain 295..543 CDD:473864
Blue background indicates that the domain is not in the aligned region.

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