DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and Tec

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_001106931.1 Gene:Tec / 21682 MGIID:98662 Length:630 Species:Mus musculus


Alignment Length:150 Identity:50/150 - (33%)
Similarity:82/150 - (54%) Gaps:21/150 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRA-ELDGKEGLIPSNYI------EMKNHDWY 61
            :|.:||.||...:|...:.|...||. ::|.:|:|| :..|.||.|||||:      .:..::||
Mouse   184 VAMYDFQATEAHDLRLERGQEYIILE-KNDLHWWRARDKYGSEGYIPSNYVTGKKSNNLDQYEWY 247

  Fly    62 YGRITRADAEKLL-SNKHEGAFLIRISESSPGDFSLSV------KCPDGVQHFKVLRDAQS--KF 117
            .....|:.||:|| :...||.|::|.| |.||.:::|:      :...|.:|:.:...|.|  |:
Mouse   248 CRNTNRSKAEQLLRTEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKY 311

  Fly   118 FLWVVK--FNSLNELVEYHR 135
            :| ..|  |.|:.|::|||:
Mouse   312 YL-AEKHAFGSIPEIIEYHK 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 20/49 (41%)
SH2_Grb2_like 56..149 CDD:199828 29/90 (32%)
SH3_GRB2_like_C 156..208 CDD:212739
TecNP_001106931.1 PH_Btk 7..148 CDD:269944
SH3_Tec 182..236 CDD:212838 21/52 (40%)
SH2_Tec_Itk 239..346 CDD:198259 29/93 (31%)
PTKc_Tec_Rlk 364..623 CDD:270685
Blue background indicates that the domain is not in the aligned region.

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