Protein Alignment drk and Src

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: XP_006499126.1
• Gene: Src / 20779
• MGIID: 98397
• Length: 552
• Species: Mus musculus
• Alignment Length: 231
• Identity: 63/231 - (27%)
• Similarity: 110/231 - (47%)
• Gaps: 54/231 - (23%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILN----------------MEDDSNWYRAE--LDGKEGLIPS 50
            :|.:|:.:..:.:|||:|.:.|:|:|                ::.:.:|:.|.  ..|:.|.|||
Mouse    89 VALYDYESRTETDLSFKKGERLQIVNNTRKVDVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPS 153

  Fly    51 NYI----EMKNHDWYYGRITRADAEKLLSNKH--EGAFLIRISESSPGDFSLSVKCPD-----GV 104
            ||:    .::..:||:|:|||.::|:||.|..  .|.||:|.||::.|.:.|||...|     .|
Mouse   154 NYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNV 218

  Fly   105 QHFKVLRDAQSKFFLWV-VKFNSLNELVEY---------HRTASVSRSQDVKLRDMIPEEMLVQA 159
            :|:|:.:.....|::.. .:||||.:||.|         ||..:|..:...:.:.:..:..
Mouse   219 KHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAW---- 279

  Fly   160 LYDFVPQESGELDFRRGDVITVTDRSDENW---WNG 192
               .:|:||..|:.:.|.     ....|.|   |||
Mouse   280 ---EIPRESLRLEVKLGQ-----GCFGEVWMGTWNG 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/66 (26%)
		SH2_Grb2_like	56..149	CDD:199828	35/109 (32%)
		SH3_GRB2_like_C	156..208	CDD:212739	10/40 (25%)
Src	XP_006499126.1	SH3_Src	87..159	CDD:212941	18/69 (26%)
		SH2_Src_Src	163..263	CDD:198228	34/99 (34%)
		PTKc_Src	276..552	CDD:270656	10/44 (23%)