Protein Alignment drk and Y47G6A.5

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_491175.2
• Gene: Y47G6A.5 / 189992
• WormBaseID: WBGene00021635
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 226
• Identity: 50/226 - (22%)
• Similarity: 91/226 - (40%)
• Gaps: 42/226 - (18%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGK-EGLIPSNYIEMKNH--DWYYGRI 65
            |.::.|.|....|:|..:..:|.::...:...||.|....: :|.:|.:::....:  .|:.|.|
 Worm   144 IVENRFLAQTPKEMSVEEGDVLYLIEQSNREWWYVASKSRQFKGFVPKSHVVYAEYREPWFAGNI 208

  Fly    66 TRADAEKLLSNKH--EGAFLIRISESSPGD-FSLSVKCP--DGVQHFKVLRDAQSKFF------- 118
            :...||:.:....  .|:||||  |:|..| |.|.|:..  :..|.:.:.|....:.|
 Worm   209 SSILAEQRVMQPQLPIGSFLIR--ENSKTDTFVLVVRSSHNESPQAYIIYRRPNQEGFEIRDNHR 271

  Fly   119 LWVVKFNSLNELVEYHRTASVSRSQDV-----KLRDMIPEEMLVQALYDFVPQESGELDFRRGDV 178
            ..|:.|.||::||.::....|.....:     |....:||:....|:        .::...|.:|
 Worm   272 PAVIHFGSLHQLVNHYSCEKVPGEIQICTKLTKAAPPLPEQTEYMAM--------KKIHVNRSEV 328

  Fly   179 ITVTDRSDENWWNGEIGNRKGIFPATYVTPY 209
            ..|.          |||  :|.|...|:..:
 Worm   329 RRVK----------EIG--RGQFGEVYLAKW 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	11/49 (22%)
		SH2_Grb2_like	56..149	CDD:199828	27/111 (24%)
		SH3_GRB2_like_C	156..208	CDD:212739	10/51 (20%)
Y47G6A.5	NP_491175.2	SH3	151..194	CDD:473055	9/42 (21%)
		SH2	202..287	CDD:198173	25/86 (29%)
		PTKc	332..601	CDD:270623	6/28 (21%)