DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and F23C8.7

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_490975.1 Gene:F23C8.7 / 184892 WormBaseID:WBGene00017736 Length:417 Species:Caenorhabditis elegans


Alignment Length:160 Identity:35/160 - (21%)
Similarity:73/160 - (45%) Gaps:34/160 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 EMKNHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGD---FSLSVKCPD-----GVQHFKVL 110
            ::.:..||:|.:.|.|.:.:|  :..|.||:|.:|...|:   :.||....:     ||:|:.:.
 Worm     5 DIHSEHWYHGLLPREDIKAML--RKNGDFLVRSTEPKAGEPRQYVLSAMQSEELEDAGVKHYVMR 67

  Fly   111 RDAQSKFFLWVVKFNSLNELVEYHRTASVSRSQDVKLRDMIPEEMLVQALYDF------VPQESG 169
            .::.::.||....|.::..||.|:    :|..:.:|...::...:|.|. ::.      :.::.|
 Worm    68 LNSSNQIFLEAKGFETIASLVNYY----MSSKEPIKKLTVLKTPILKQP-WEIEHSQVELTKKLG 127

  Fly   170 ELDFRRGDVITVTDRSDENWWNGEIGNRKG 199
            |..|  |:|           |.|::..:.|
 Worm   128 EGAF--GEV-----------WKGKLTLKNG 144

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738
SH2_Grb2_like 56..149 CDD:199828 25/100 (25%)
SH3_GRB2_like_C 156..208 CDD:212739 10/50 (20%)
F23C8.7NP_490975.1 SH2_Fps_family 4..98 CDD:198224 24/98 (24%)
TyrKc 120..374 CDD:197581 8/38 (21%)
Blue background indicates that the domain is not in the aligned region.

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