Protein Alignment drk and Grap2

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001276371.1
• Gene: Grap2 / 17444
• MGIID: 1333842
• Length: 322
• Species: Mus musculus
• Alignment Length: 321
• Identity: 105/321 - (32%)
• Similarity: 146/321 - (45%)
• Gaps: 115/321 - (35%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            |||.||.||.|:.:||||||...|||||:.:::  |.:|||..:||.:|.|:|:::..:|::..:
Mouse     1 MEATAKFDFMASGEDELSFRTGDILKILSNQEE--WLKAELGSQEGYVPKNFIDIEFPEWFHEGL 63

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|..||.||..|..|.|:||.|:|||||||:||:..|.||||||:||.:..:|||..||.|||:|
Mouse    64 SRHQAENLLMGKDIGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDTKGNYFLWTEKFPSLNKL 128

  Fly   131 VEYHRTASVSRSQDVKLRD------------------------MIPEEM---------------- 155
            |:|:||.|:|:.:.|.|||                        .:.||:
Mouse   129 VDYYRTTSISKQKQVFLRDGTQDQGHRGNSLDRRSQGGPHPSGTVGEEIRPSVNRKLSDHLPLGP 193

  Fly   156 ----------------------------------------------------------------- 155
                                                                             
Mouse   194 QQFHPHQQPSPQFTPGPQPPQQQRYLQHFHQDRRGGSLDINDGHCGLGSEVNATLMHRRHTDPVQ 258

  Fly   156 --------LVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYVTP 208
                    ..:|||||...|..||.||.|:|:.|.|.|:.:||.|.:.|:.|:|||.||.|
Mouse   259 LQAAGRVRWARALYDFEALEEDELGFRSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAP 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	26/50 (52%)
		SH2_Grb2_like	56..149	CDD:199828	47/92 (51%)
		SH3_GRB2_like_C	156..208	CDD:212739	25/51 (49%)
Grap2	NP_001276371.1	SH3	2..53	CDD:302595	27/52 (52%)
		SH2_Grb2_like	54..147	CDD:199828	47/92 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..216		6/72 (8%)
		SH3_GRAP2_C	267..319	CDD:212883	25/51 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091250at2759
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X588
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020