DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and src-2

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_493502.1	Gene:	src-2 / 173296	WormBaseID:	WBGene00005078	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	144	Identity:	56/144 - (38%)
Similarity:	86/144 - (59%)	Gaps:	11/144 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWY-RAELDGKEGLIPSNYI----EMKNHDWYYG 63
            :|...:.|..||:|||:|..||:|||......|: |.:..|:.|.|||||:    .:::..||:|
Worm    63 VALFQYDARTDDDLSFKKDDILEILNDTQGDWWFARHKATGRTGYIPSNYVAREKSIESQPWYFG 127

  Fly    64 RITRADAEKLL---SNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVK-F 124
            ::.|.||||.|   .|:| ||||:|.|||...|.||||:..|.|:|:::.:.....:|:...: |
Worm   128 KMRRIDAEKCLLHTLNEH-GAFLVRDSESRQHDLSLSVRENDSVKHYRIRQLDHGGYFIARRRPF 191

  Fly   125 NSLNELV-EYHRTA 137
            .:|::|: .|.|.|
Worm   192 ATLHDLIAHYQREA 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	21/49 (43%)
		SH2_Grb2_like	56..149	CDD:199828	34/87 (39%)
		SH3_GRB2_like_C	156..208	CDD:212739
src-2	NP_493502.1	SH3_Src_like	61..112	CDD:212779	20/48 (42%)
		SH2_Src_Src42	120..215	CDD:198233	34/87 (39%)
		PTKc_Frk_like	231..496	CDD:270653
		Pkinase_Tyr	240..489	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910