Protein Alignment drk and unc-57

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_001122513.1
• Gene: unc-57 / 172078
• WormBaseID: WBGene00006791
• Length: 381
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 61/268 - (22%)
• Similarity: 96/268 - (35%)
• Gaps: 86/268 - (32%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||...|.:|.    |.|:..:...||      |.|.:|.:|.|:.    .:|...|........:
 Worm   131 MEDNVKQNFL----DPLTHLQNNELK------DVNHHRTKLKGRR----LDYDCKKRQQRRDDEM 181

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVK-FNSLNE 129
            .:|: |||..:|       |::|.|.  |::.....:.:...:.|.:||..|.....: ..:|.:
 Worm   182 IQAE-EKLEESK-------RLAEMSM--FNVLSNDVEQISQLRALIEAQLDFHRQTAQCLENLQQ 236

  Fly   130 LV------------EYHRTASV----SRSQDVKLRDMIPEEM----------------------- 155
            .:            |.|...||    ||:.....|...|.:|
 Worm   237 QLGHRIKDAAARPREEHVPLSVLANESRTPRSSFRSPAPSDMSHNSTAAAAFKMPPQNGGGITQA 301

  Fly   156 ----------------------LVQALYDFVPQESGELDFRRGDVITVTDRSDENWWNGEIGNRK 198
                                  ..:||:||..|..|||||:.|.:|.:..:.||||:.|.:..:.
 Worm   302 PPSYQGPPPGGLPPPLSQQQKPQCRALFDFDAQSEGELDFKEGTLIELVSQIDENWYEGRVNGKT 366

  Fly   199 GIFPATYV 206
            |:||.|||
 Worm   367 GLFPVTYV 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	12/50 (24%)
		SH2_Grb2_like	56..149	CDD:199828	21/109 (19%)
		SH3_GRB2_like_C	156..208	CDD:212739	23/51 (45%)
unc-57	NP_001122513.1	BAR_Endophilin_A	25..245	CDD:153276	29/137 (21%)
		SH3_Endophilin_A	323..377	CDD:212737	23/52 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R571
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030