Protein Alignment drk and cdap-2

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_491143.3
• Gene: cdap-2 / 171906
• WormBaseID: WBGene00021549
• Length: 551
• Species: Caenorhabditis elegans
• Alignment Length: 225
• Identity: 53/225 - (23%)
• Similarity: 98/225 - (43%)
• Gaps: 51/225 - (22%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAEL--DGKEGLIPSNYIEMK---------- 56
            :|.:.:|:..||||||....::::::..:| .|.:.:|  .|..|:.|:|::.:|
 Worm    52 VATYAYSSKQDDELSFVVGDLIELISDVED-GWSKGKLKSTGAVGMFPTNFVTLKPTPSTSAAAV 115

  Fly    57 ----NHDWYYGRITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKF 117
                :.....|...|..|:.:      |:.::..||....|.:.|....|.....|.|.
 Worm   116 APAASASTSAGSAARTPAKSI------GSEVVMRSEPKAIDRTPSTIISDPAPVLKALE------ 168

  Fly   118 FLWVVKFNSLNELVEYHRTASVSRSQD---VKLRDMIPEEMLVQALYDFVPQESGELDFRRGD-V 178
                .||:|.      ..:::.|.|.|   .|.::|    ..|:.:|:  ||...||..:..| :
 Worm   169 ----TKFSST------FASSAASASTDAETTKTKEM----ARVKFVYN--PQHDDELALKEIDML 217

  Fly   179 ITVTDRS--DENWWNGEIGNRKGIFPATYV 206
            |.:|:::  |..|:.||:..:||:||..:|
 Worm   218 INITNKNCGDAGWFEGELHGKKGLFPDNFV 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	15/50 (30%)
		SH2_Grb2_like	56..149	CDD:199828	19/109 (17%)
		SH3_GRB2_like_C	156..208	CDD:212739	18/54 (33%)
cdap-2	NP_491143.3	SH3	53..104	CDD:473055	15/51 (29%)
		SH3	194..249	CDD:473055	19/60 (32%)