DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment drk and src-1

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_001364829.1 Gene:src-1 / 171722 WormBaseID:WBGene00005077 Length:537 Species:Caenorhabditis elegans


Alignment Length:146 Identity:46/146 - (31%)
Similarity:83/146 - (56%) Gaps:15/146 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWY-RAELDGKEGLIPSNYI----EMKNHDWYYG 63
            :|.:.:.:.||.:|||:|...:.:|:..:...|| |.:..|:.|.:|.|::    .:::.:||.|
 Worm    81 VALYPYDSRADGDLSFQKGDAMYLLDHSNCDWWYVRHQRTGQTGYVPRNFVAKQQTIESEEWYAG 145

  Fly    64 RITRADAEKLLSNKH--EGAFLIRISESSPGDFSLSVKCPDG------VQHFKVLR-DAQSKFFL 119
            :|.|..||:|:.:.|  :|.||||..|:...:|:|:::..|.      |:|:|:.| |....:|:
 Worm   146 KIPRNRAERLVLSSHLPKGTFLIREREADTREFALTIRDTDDQRNGGTVKHYKIKRLDHDQGYFI 210

  Fly   120 WVVK-FNSLNELVEYH 134
            ...: |.||.|||.|:
 Worm   211 TTRRTFRSLQELVRYY 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 15/49 (31%)
SH2_Grb2_like 56..149 CDD:199828 31/89 (35%)
SH3_GRB2_like_C 156..208 CDD:212739
src-1NP_001364829.1 SH3_Src_like 79..130 CDD:212779 14/48 (29%)
SH2_Src_family 138..240 CDD:199827 31/89 (35%)
PTKc_Src_like 270..522 CDD:270630
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.