DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and Lyn

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_001104566.1	Gene:	Lyn / 17096	MGIID:	96892	Length:	512	Species:	Mus musculus

Alignment Length:	149	Identity:	47/149 - (31%)
Similarity:	85/149 - (57%)	Gaps:	16/149 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE-LDGK-EGLIPSNYI----EMKNHDWYY 62
            :|.:.:.....|:|||:|.:.:|:|  |:...|::|: |..| ||.|||||:    .::..:|::
Mouse    69 VALYPYDGIHPDDLSFKKGEKMKVL--EEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFF 131

  Fly    63 GRITRADAEK--LLSNKHEGAFLIRISESSPGDFSLSVK-----CPDGVQHFKVLRDAQSKFFLW 120
            ..|||.|||:  |......||||||.||:..|.|||||:     ..|.::|:|:.......:::.
Mouse   132 KDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYIS 196

  Fly   121 V-VKFNSLNELVEYHRTAS 138
            . :.|..:::::::::..|
Mouse   197 PRITFPCISDMIKHYQKQS 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	19/50 (38%)
		SH2_Grb2_like	56..149	CDD:199828	27/91 (30%)
		SH3_GRB2_like_C	156..208	CDD:212739
Lyn	NP_001104566.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
		SH3_Lyn	67..122	CDD:212937	20/54 (37%)
		SH2_Src_Lyn	125..225	CDD:198227	27/91 (30%)
		PTKc_Lyn	239..510	CDD:270657
		Pkinase_Tyr	247..497	CDD:285015
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910