Protein Alignment drk and Blk

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_031575.2
• Gene: Blk / 12143
• MGIID: 88169
• Length: 499
• Species: Mus musculus
• Alignment Length: 184
• Identity: 56/184 - (30%)
• Similarity: 100/184 - (54%)
• Gaps: 20/184 - (10%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWY--RAELDGKEGLIPSNYI----EMKNHDWYY 62
            :|..|::|..|.:|...|.:.|::|....|  |:  |:.:.|:||.:|||::    .::...|::
Mouse    58 VALFDYAAVNDRDLQVLKGEKLQVLRSTGD--WWLARSLVTGREGYVPSNFVAPVETLEVEKWFF 120

  Fly    63 GRITRADAEKLL---SNKHEGAFLIRISESSPGDFSLSVK--CPDG--VQHFKVLRDAQSKFFLW 120
            ..|:|.|||:.|   .|| .|:||||.|||:.|.||||||  ...|  |:|:|:.......:::.
Mouse   121 RTISRKDAERQLLAPMNK-AGSFLIRESESNKGAFSLSVKDITTQGEVVKHYKIRSLDNGGYYIS 184

  Fly   121 V-VKFNSLNELVEYHRTASVSRSQDVKLR--DMIPEEMLVQALYDFVPQESGEL 171
            . :.|.:|..||:::........|.:.|.  ::.|:.:..|..:: :|::|.:|
Mouse   185 PRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAPKNLWAQDEWE-IPRQSLKL 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	17/50 (34%)
		SH2_Grb2_like	56..149	CDD:199828	34/102 (33%)
		SH3_GRB2_like_C	156..208	CDD:212739	4/16 (25%)
Blk	NP_031575.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34
		SH3	56..109	CDD:473055	17/52 (33%)
		SH2_Src_Blk	114..213	CDD:198234	33/99 (33%)
		Protein Kinases, catalytic domain	227..490	CDD:473864	3/12 (25%)