Protein Alignment drk and GRAP

DIOPT Version :9

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_006604.1
• Gene: GRAP / 10750
• HGNCID: 4562
• Length: 217
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 119/219 - (54%)
• Similarity: 150/219 - (68%)
• Gaps: 12/219 - (5%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            ||::|.:.|.||..|||:|.|...|||||||||.|||:|||.|.||.||.|||.:|.|.||.|||
Human     1 MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRI 65

  Fly    66 TRADAEKLLSNK-HEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNE 129
            :|..||::|..: |.||||||.||||||:||:||...|.||||||||:|..|:|||..|||||||
Human    66 SRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNE 130

  Fly   130 LVEYHRTASVSRSQDVKLRDMIPEEMLV--------QALYDFVPQESGELDFRRGDVITVTDRSD 186
            ||:::||.::::.:.:.|||   ||.|:        ||.:||..|:..:|.|||||:|.|.:|.|
Human   131 LVDFYRTTTIAKKRQIFLRD---EEPLLKSPGACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPD 192

  Fly   187 ENWWNGEIGNRKGIFPATYVTPYH 210
            .:||.|....|.|.||.:||.|.|
Human   193 PHWWRGRSCGRVGFFPRSYVQPVH 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	31/50 (62%)
		SH2_Grb2_like	56..149	CDD:199828	54/93 (58%)
		SH3_GRB2_like_C	156..208	CDD:212739	25/59 (42%)
GRAP	NP_006604.1	SH3_GRAP_N	2..55	CDD:212881	33/52 (63%)
		SH2_Grb2_like	56..150	CDD:199828	54/93 (58%)
		SH3_GRAP_C	162..214	CDD:212884	24/51 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46063
OrthoDB	1	1.010	-	-		D1091250at2759
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46037
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X588
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	7.030