Protein Alignment drk and sla2

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: XP_002939613.1
• Gene: sla2 / 100495864
• XenbaseID: XB-GENE-6257915
• Length: 269
• Species: Xenopus tropicalis
• Alignment Length: 236
• Identity: 58/236 - (24%)
• Similarity: 103/236 - (43%)
• Gaps: 54/236 - (22%)

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAE--LDGKEGLIPSNYIEMKNHDWYYGRIT 66
            :|.::|......:||.|..:.|.||:  :|.:|.:..  ..|.|..:|:||:....:.|.|..|.
 Frog    36 VALYNFPLGGQTDLSIRFGEQLNILS--EDGDWLKVSSLSTGHECYLPTNYVAKVCNRWLYRGIN 98

  Fly    67 RADAEKLL--SNKHEGAFLIRISESSPGDFSLSVK-----CPDGVQHFKVLRDAQSKFFLWV-VK 123
            |..||:||  ::...|:||||.||:..|.::||::     ..|.::|:::.:.....|::.. :.
 Frog    99 REKAEELLMVNSNQSGSFLIRESETRSGSYTLSIRKTSQSSRDSIKHYRIHQLDNGWFYIAPRLT 163

  Fly   124 FNSLNELVEYH-----------RTASVSR--SQDVKLRDMIPEEMLVQALYDFVPQESGELD-FR 174
            |.:|.::|:|:           |.|.|.:  |..|..|   |.|.:|........:|...|| |.
 Frog   164 FATLQDMVDYYSEVADGICCTLREACVVQRVSNPVIQR---PSEPIVVRKPTLNWKELDSLDLFN 225

  Fly   175 RGDVI-------------------------TVTDRSDENWW 190
            :.|.:                         ::|:...|:||
 Frog   226 KEDKLNEDCPVSLGLREAVSSYMLMTQDSDSMTEVEKEHWW 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	14/50 (28%)
		SH2_Grb2_like	56..149	CDD:199828	30/113 (27%)
		SH3_GRB2_like_C	156..208	CDD:212739	10/61 (16%)
sla2	XP_002939613.1	SH3_SLAP2	34..88	CDD:212944	15/53 (28%)
		SH2_SLAP	81..184	CDD:198207	28/102 (27%)