Protein Alignment drk and grap2

DIOPT Version :10

• Sequence 1: NP_476858.1
• Gene: drk / 36497
• FlyBaseID: FBgn0004638
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: XP_002933793.1
• Gene: grap2 / 100492322
• XenbaseID: XB-GENE-6086850
• Length: 301
• Species: Xenopus tropicalis
• Alignment Length: 298
• Identity: 105/298 - (35%)
• Similarity: 150/298 - (50%)
• Gaps: 94/298 - (31%)

  Fly     1 MEAIAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYIEMKNHDWYYGRI 65
            |||.|.::|:|:.:|||||:|..:||||:.:|  |||::||:|.||.:|.||:|:....||...|
 Frog     1 MEAQAMYEFNASGEDELSFKKGDVLKILSSDD--NWYKSELNGSEGYVPKNYVEVHFPRWYCENI 63

  Fly    66 TRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWVVKFNSLNEL 130
            :|.:||.:|..:..|||:||.|::|.|:||:||:..|.||||||:||.:..::||..||.|||:|
 Frog    64 SRGEAESILIGRFVGAFIIRASQTSKGEFSMSVRDEDDVQHFKVMRDIRGNYYLWTEKFKSLNKL 128

  Fly   131 VEYHRTASVSRSQDVKLRD---------------------------MIP---------------- 152
            |||::|||:||.:::.||:                           ::|
 Frog   129 VEYYKTASISRQKEIYLREEGSEAQEKLVEKHVRDPRSSGGGRAGKLMPAGSQRNYPEPETDRTK 193

  Fly   153 -----------------------EE--------------------------MLVQALYDFVPQES 168
                                   ||                          .:|:|||||...|.
 Frog   194 CVSSKPSGAPPEARHQNPVAQASEECSKIPSSYKGPSNPQRAQASPTPQRIRMVKALYDFQAMEP 258

  Fly   169 GELDFRRGDVITVTDRSDENWWNGEIGNRKGIFPATYV 206
            .||.|...|||.|.|.||.:||.|.:|.|.|:||:.||
 Frog   259 DELGFIYSDVIEVLDCSDASWWMGRLGERVGLFPSNYV 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	26/50 (52%)
		SH2_Grb2_like	56..149	CDD:199828	45/92 (49%)
		SH3_GRB2_like_C	156..208	CDD:212739	27/51 (53%)
grap2	XP_002933793.1	SH3_GRAP2_N	2..53	CDD:212880	27/52 (52%)
		SH2_Grb2_like	54..147	CDD:199828	45/92 (49%)
		SH3_GRAP2_C	246..298	CDD:212883	27/51 (53%)