DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and sla

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	XP_002939560.1	Gene:	sla / 100491564	XenbaseID:	XB-GENE-6073731	Length:	277	Species:	Xenopus tropicalis

Alignment Length:	221	Identity:	55/221 - (24%)
Similarity:	97/221 - (43%)	Gaps:	35/221 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DFSATADDELSFRKTQILKILNMEDDSNWYR--AELDGKEGLIPSNYIEMKNHDWYYGRITRADA 70
            |:.:....|..|...:.|::::  |:..|:|  :...|:|..||:..:....|.|.:..:.|..:
Frog    32 DYPSPDVSEPIFNFGEKLRVIS--DEGGWWRVVSLRTGRENYIPAKCVAKVYHGWLFEGVGREKS 94

  Fly    71 EKLLS--NKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWV-VKFNSLNELVE 132
            |:||.  :...|:|:||.||:..|.:||||| ...|:|:::.|...|.|::.. :.|..|..||.
Frog    95 EELLQLPDTKNGSFMIRQSETEKGSYSLSVK-HRHVKHYRIFRLPNSWFYISPRLTFQCLEHLVN 158

  Fly   133 YHR----------TASVSRSQDVKLRDMIPEEMLVQALYDFVP---QESGELDFRRGDVITVTDR 184
            ::.          |:.....|.:...|         ||...||   :.....|:|....:.:|..
Frog   159 HYSEYADGLCCVLTSPCLTQQSINYTD---------ALNHQVPPVVRRRRPFDWRSTKRVPLTME 214

  Fly   185 SDENWWNG---EIGNRKGIFPATYVT 207
            ..||..:.   ..|.|:.|  |:|::
Frog   215 EPENSLDDTFLSYGLRQSI--ASYIS 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	11/46 (24%)
		SH2_Grb2_like	56..149	CDD:199828	29/105 (28%)
		SH3_GRB2_like_C	156..208	CDD:212739	14/58 (24%)
sla	XP_002939560.1	SH3_SLAP	26..80	CDD:212943	11/49 (22%)
sla	XP_002939560.1	SH2_SLAP	73..170	CDD:198207	28/97 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910