DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and frk

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	XP_002938349.1	Gene:	frk / 100488362	XenbaseID:	XB-GENE-492884	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	142	Identity:	49/142 - (34%)
Similarity:	83/142 - (58%)	Gaps:	12/142 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAEL---DGK-EGLIPSNYI----EMKNHDW 60
            :|.:.:.....|||||:....:.|:: ...::|::|:|   .|| ||.:|.||:    .:::..|
Frog    66 VALYSYEGRTPDELSFKAGDQMLIID-TTHASWWKAKLLRTRGKAEGYVPFNYVAPVSSIESMPW 129

  Fly    61 YYGRITRADAEKLL--SNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLW-VV 122
            ::..|.|::||:||  .....|:||||.|||..|::||||.....|:|:::.:.....|::. ..
Frog   130 FFKDIKRSEAERLLVRPGNTTGSFLIRESESQKGEYSLSVFDGIAVKHYRLRKLDDGGFYITSKS 194

  Fly   123 KFNSLNELVEYH 134
            ||.|:||||||:
Frog   195 KFVSMNELVEYY 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	16/52 (31%)
		SH2_Grb2_like	56..149	CDD:199828	32/82 (39%)
		SH3_GRB2_like_C	156..208	CDD:212739
frk	XP_002938349.1	SH3_Src_like	65..117	CDD:212779	15/51 (29%)
		SH2	125..220	CDD:387587	32/82 (39%)
		PTKc_Frk_like	238..505	CDD:270653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910