DRSC/TRiP Functional Genomics Resources

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Protein Alignment drk and abl2

DIOPT Version :10

Sequence 1:NP_476858.1 Gene:drk / 36497 FlyBaseID:FBgn0004638 Length:211 Species:Drosophila melanogaster
Sequence 2:XP_002937405.1 Gene:abl2 / 100487790 XenbaseID:XB-GENE-6459814 Length:1100 Species:Xenopus tropicalis


Alignment Length:140 Identity:50/140 - (35%)
Similarity:82/140 - (58%) Gaps:5/140 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 IAKHDFSATADDELSFRKTQILKILNMEDDSNWYRAELDGKEGLIPSNYI----EMKNHDWYYGR 64
            :|.:||.|:.|:.||..|.:.|::|....:..|........:|.:|||||    .::.|.||:|.
 Frog   102 LALYDFVASGDNTLSITKGEKLRVLCYNQNGEWCEVLSKNGQGWVPSNYITPVNSLEKHSWYHGP 166

  Fly    65 ITRADAEKLLSNKHEGAFLIRISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWV-VKFNSLN 128
            ::|:.||.|||:...|:||:|.||||||..|:|::....|.|:::...:..|.::.. .:||:|.
 Frog   167 VSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTASDGKVYVTAESRFNTLA 231

  Fly   129 ELVEYHRTAS 138
            |||.:|.|.:
 Frog   232 ELVHHHSTVA 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
drkNP_476858.1 SH3_GRB2_like_N 2..53 CDD:212738 15/48 (31%)
SH2_Grb2_like 56..149 CDD:199828 33/84 (39%)
SH3_GRB2_like_C 156..208 CDD:212739
abl2XP_002937405.1 SH3_Abl 100..153 CDD:212784 17/50 (34%)
SH2_ABL 158..251 CDD:198189 33/84 (39%)
PTKc_Abl 270..532 CDD:270645
F_actin_bind 984..1100 CDD:471692
Blue background indicates that the domain is not in the aligned region.

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