DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment drk and si:ch73-340m8.2

DIOPT Version :9

Sequence 1:	NP_476858.1	Gene:	drk / 36497	FlyBaseID:	FBgn0004638	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	XP_002665190.3	Gene:	si:ch73-340m8.2 / 100332982	ZFINID:	ZDB-GENE-110411-209	Length:	480	Species:	Danio rerio

Alignment Length:	167	Identity:	41/167 - (24%)
Similarity:	80/167 - (47%)	Gaps:	32/167 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ELSFRKTQILKILNMEDDSNWY-----RAELD------GKEGLIPSNYIE----MKNHDWYYGRI 65
            :|:.||..||::..  :...|.     .|:.|      .:.|.:|.::::    ::...||:..:
Zfish    46 DLNLRKGDILEVTG--ETEYWLYVRRRTAKTDKSKSFIEEHGYVPKDFVKPLDSVEAEPWYFENV 108

  Fly    66 -TRADAEKLL---SNKHEGAFLI-RISESSPGDFSLSVKCPDGVQHFKVLRDAQSKFFLWV--VK 123
             ||.:|::.|   .|| |||||: :..|::  .:.||||.....:|:::.:....:.|..|  ..
Zfish   109 KTRVEAKRCLLRPENK-EGAFLVWKCDENN--HYYLSVKNGPHARHYRIKQGENDQQFFLVHHTT 170

  Fly   124 FNSLNELVEY---HRTASVSRSQD--VKLRDMIPEEM 155
            |.||.:|:|:   |.....::..:  |||...:|:.:
Zfish   171 FQSLRKLIEFYSKHEGGLCAKLHEACVKLDQPVPQTL 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
drk	NP_476858.1	SH3_GRB2_like_N	2..53	CDD:212738	10/47 (21%)
		SH2_Grb2_like	56..149	CDD:199828	30/104 (29%)
		SH3_GRB2_like_C	156..208	CDD:212739	41/167 (25%)
si:ch73-340m8.2	XP_002665190.3	SH2	99..192	CDD:301589	27/95 (28%)
		Pkinase_Tyr	220..468	CDD:285015
		PKc_like	225..468	CDD:304357
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000